Lavender (Lavandula stoechas) essential oils attenuate Lambda-Cyhalothrin induced liver damage in Rabbit

Abstract

The health consequences of pesticide exposure are a frequent concern for population, and essential oils are used in phytotherapy. This study was carried out to determine the detoxifying effect of Lavandula stoechas essential oil (LS.EO) against the insecticide Lambda-Cyhalothrin (LCT) in the rabbit Cuniculus lepus. Which they were divided into a control group, a group treated with (LCT) (100mg/Kg/BW), and the last group with the combination of (100 mg/Kg/BW LCT+500 mg/Kg/BW.LS.EO). LCT and LS.EO were administered orally via diet for one month. Serum biomarkers were assessed. Results showed a highly significant increase in CRP levels in both treated groups compared with control. Blood glucose, TC, and HDL levels showed no significant differences. On the other hand, the two groups treated with LCT and LCT+LS.EO showed a very significant increase in LDL and TG levels compared to control. However, the combined treatment reduced toxicity (LCT) by recording significant changes in most of the biochemical markers studied.