Inhibition of cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) by D-005 (A lipid extract of Acrocomia crispa fruits)

Authors

  • Yohani Pérez
  • Ambar Oyarzábal
  • Roxana Sierra
  • Rosa Mas
  • Vivian Molina
  • Sonia Jiménez
  • Victor González

Keywords:

Acrocomia crispa, Anti-inflammatory, COX, Dual inhibition, 5-LOX

Abstract

This study was aimed to investigate whether the a lipid extract from Acrocomia crispa fruits (D-005) inhibits COX and 5-LOX enzyme activities in vitro. This study demonstrates that D-005 inhibits markedly and in a dose dependent manner COX-2 and 5-LOX activities. The dual inhibition of COX-2 and 5-LOX supports further research on the potential anti-inflammatory effect of D-005.

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Published

2017-05-30

How to Cite

Pérez, Y., Oyarzábal, A., Sierra, R., Mas, R., Molina, V., Jiménez, S., & González, V. (2017). Inhibition of cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) by D-005 (A lipid extract of Acrocomia crispa fruits). Boletín Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromáticas, 16(3), 319-328. Retrieved from https://blacpma.ms-editions.cl/index.php/blacpma/article/view/187

Issue

Vol. 16 No. 3: May 2017

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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