Phytochemical analysis and antioxidant activities of Indigofera oblongifolia, local plant extract used in traditional medicine: Antimalarial activities

Abstract

The use of eco-friendly natural products is one of the major areas of research that has anticoccidial properties. This investigation aims to identify and evaluate the bioactive constituents of the Indigofera oblongifolia leaf extract (IOLE), as an antimalarial. Fourier Transform Infrared Spectroscopy
(FTIR) was used to determine any significant information about the functional groups, as well as assays for total phenolics, tannins, total flavonoids, DPPH, ABTS tests, XRD, and UV-VIS Spectroscopic analysis. The results of FTIR analysis of the extract showed the presence of 5 phytochemical compounds.
Moreover, the quantitative analysis revealed that the concentrations of phenols, tannins, and flavonoids were, 219.106 ± 1.0792, 89.438 ± 0.1599, and 19 ± 0.1500 (mg TAE/g DW), respectively. The results obtained indicate that these extracts have a high level of antioxidant activity and the scavenging activity
of DPPH radicals. The UV-VIS showed varying absorbances between 300 and 800 nm. The IOLE proved effective against Plasmodium berghei in mice.