Seasonal variance in the chemical composition of essential oils from Lantana camara accessions and their trypanocidal activity on Phytomonas serpens

Abstract

The objective of this study was to investigate the seasonal variance of the content and chemical composition of the essential oil from Lantana camara accessions at two harvest times, and to analyze the trypanocidal activity on Phytomonas serpens. Essential oil content ranged from 0.13 to 0.29% in the rainy season and from 0.13 to 0.33% in the dry season. The compounds E-caryophyllene, α-humulene, α-curcumene and germacrene D defined the formation of four chemical clusters in the rainy and dry seasons, classified as: Cluster 1 (E-caryophyllene + germacrene D); Cluster 2 (germacrene D + E-caryophyllene); Cluster 3 (α-humulene + E-caryophyllene); and Cluster 4 (α-curcumene + E-caryophyllene). All L. camara essential oils, representing the four chemical clusters, inhibited P. serpens with low concentrations, considering the following IC50 values: 18.34 ± 6.60 μg/mL (LAC-018, Cluster 1); 9.14 ± 3.87 μg/mL (LAC-027, Cluster 2); 14.56 ± 3.40 μg/mL (LAC-037, Cluster 3); and 14.97 ± 2.68 μg/mL (LAC-019, Cluster 4).